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In addition, its cellular and mitochondrial levels directly correlate with health and longevity

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For example, due to the downregulation of genes for purinergic receptors (e.g., P2ry12 ) and potassium leak channels (e.g., Thik-1 ) in aged mice, the ability for microglia to sense hyperactive neurons and migrate toward them in order to facilitate rapid repolarization would be reduced, impairing their beneficial modulation (Hickman et al., 2013

suggesting potential variations in quality from batch to batch